منابع مشابه
Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations
Cancer drug screening in patient-derived cells holds great promise for personalized oncology and drug discovery but lacks standardization. Whether cells are cultured as conventional monolayer or advanced, matrix-dependent organoid cultures influences drug effects and thereby drug selection and clinical success. To precisely compare drug profiles in differently cultured primary cells, we develop...
متن کاملOrganoid technology for retinal repair.
A major cause for vision impairment and blindness in industrialized countries is the loss of the light-sensing retinal tissue in the eye. Photoreceptor damage is one of the main characteristics found in retinal degeneration diseases, such as Retinitis Pigmentosa or age-related macular degeneration. The lack of effective therapies to stop photoreceptor loss together with the absence of significa...
متن کاملModel-Driven Engineering Meets Generic Language Technology
One of the key points of model-driven engineering is raising the level of abstraction in software development. This phenomenon is not new. In the sixties of the previous century, the first high-level programming languages were developed and they also increased the abstraction level of software development. The development of high-level programming languages initiated research on compilers and p...
متن کاملAdvancing Intestinal Organoid Technology Toward Regenerative Medicine
With the emergence of technologies to culture intestinal epithelial cells in vitro as various forms of intestinal organoids, there is growing interest in using such cultured intestinal cells as a source for tissue engineering and regenerative medicine. One such approach would be to combine the organoid technology with methodologies to engineer the culture environment, particularly the three-dim...
متن کاملBreast Cancer Screening Behaviors Based on Health Belief Model
Abstract Introduction: The incidence and mortality of breast cancer will be reduced by screening. Objective: The study aimed to determine breast cancer screening behaviors based on the health beliefs model in women living in Mashhad City, Iran. Materials and Methods: This analytical cross-sectional study was conducted on 406 women referring to five health-medical centers in Mashhad from July...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Translational Oncology
سال: 2020
ISSN: 1936-5233
DOI: 10.1016/j.tranon.2020.100840